There are many aspects related to detoxification, one of which is your HLA haplotype.
If your DNA is flawed in certain genes, you may be less able to detoxify and more susceptible to certain triggers, such as mold and Lyme bacteria and confections. If you’re curious, you can test for these genes, but a better first step might be supporting your body nutritionally, implementing some basic binders to remove toxins and testing for which foods cause your body to become inflamed (elimination diet) or other underlying causes (with an OAT). Then, if you are still stumped as to what is causing your symptoms, an HLA Haplotype test might be helpful.
What are HLA Haplotypes?
- HLA stands for Human Leukocyte Antigen.
- A haplotype is a set of genes on the chromosomes in DNA.
- HLA haplotypes code for proteins on the outer portion of immune cells, namely those involved in antibody formation. (Antibodies help a body differentiate between “self” and “non-self”.)
- Normally, when a body sees something that is “non-self”, like a toxin or bacterium, it launches an attack. (See an immune cell chase and attack a bacterium in this amazing video)
- But, in some bodies, the coding in one or more HLA haplotypes are flawed. This makes it harder for an immune cell to recognize toxins as foreign invaders and launch an attack.
Associated Lab Tests
- Blood test for HLA genotype = Test #167120 from LabCorp
- Nutrient Deficiency Test from SpectraCell Labs
- Reveals your functional nutrient deficiencies by challenging your cells.
- No matter your DNA, your body can’t heal or fight if it doesn’t have the nutrients it needs.
- Organic Acids Test from Great Plains Labs
- Reveals other potential root causes for hampered detoxification, such as candida (which can disrupt neurotransmitter balance, prevent your beneficial flora from taking hold and increase inflammation), oxalates, subclinical clostridium bacterial infection, mitochondrial dysfunction, inborn errors of metabolism and more.
- Reference the HLA Rosetta Stone created by Ritchie Shoemaker of SurvivingMold.com.
- Set up a session at BuzzNutrition.
- Google HLA and “Mold Warriors” for a number of forums to which fellow HLA testers have posted requests and offers of help.
- Call (800)533-1037 for Doctor Uve Heine, LabCorp’s resident expert on interpretation of HLA.
- High-dose chlorella
- Take 12g/day total: 4 grams, 3 times/day, 30 minutes before meals.
- High doses are okay because chlorella is a food.
- Low doses mobilize toxins and metals but don’t bind them all, whereas high doses can bind more and pull them out of the body.
- Also effective for heavy metal removal.
- After a few months on this dose, a lower maintenance dose can be taken… some believe that in this toxic world we live in, chlorella detox should be a lifelong practice.
- Other binders: Activated charcoal, bentonite clay, fruit pectins, Alkaseltzer Gold, shilajit.
- Cholestyramine & Actos
- Less desirable than supplements since they come along with side-effects + exhaust the liver and kidneys.
- When taking cholestyramine, the diet should be supplemented with cholesterol (egg yolks, butter, fatty fish and liver).
- Avoid brand names that contain aspartame: Questran Light & Prevalite. Plain Questran and generic cholestyramine do not.